Threading intercalation to double-stranded DNA and the application to DNA sensing. Electrochemical array technique*
نویسنده
چکیده
Electrochemical labeling of double-stranded (ds) DNA is achieved by redox-active DNA intercalators. Threading intercalators derived from naphthalenediimide appended with ferrocene reporter group in the side arms are particularly useful for this purpose. This allows a sensitive electrochemical detection of DNA hybridization on an array, providing a great potential for low-cost, high-throughput, and quick DNA screening technique in post-genome study.
منابع مشابه
A redox active and electrochemiluminescent threading bis-intercalator and its applications in DNA assays.
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